Visipaque (Iodixanol) and Hexabrix (Ioxaglate) in Renal Insufficiency

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Visipaque (iodixanol) and hexabrix (ioxaglate) in renal insufficiency.

I read with great interest the RECOVER (Renal Toxicity Evaluation and Comparison Between Visipaque and Hexabrix in Patients With Renal Insufficiency Undergoing Coronary Angiography) study by Jo et al. (1). They compared the renal tolerance of iodixanol and ioxaglate in patients with renal insufficiency after coronary angiography. They found that the incidence of contrastinduced nephropathy (CIN...

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1. Jo SH, Youn TJ, Koo BK, et al. Renal toxicity evaluation and comparison between Visipaque (iodixanol) and Hexabrix (ioxaglate) in patients with renal insufficiency undergoing coronary angiography: the RECOVER study: a randomized controlled trial. J Am Coll Cardiol 2006;48:924–30. 2. Jo SH, Youn TJ, Park JS, et al. Iodixanol is less nephrotoxic than ioxaglate in patients with renal insufficie...

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Nephrotoxicity of iodixanol versus ioversol in patients with chronic kidney disease: the Visipaque Angiography/Interventions with Laboratory Outcomes in Renal Insufficiency (VALOR) Trial.

BACKGROUND Iso-osmolar contrast medium iodixanol has been reported to be less nephrotoxic than selected low-osmolar contrast media (LOCM) in chronic kidney disease (CKD) patients with diabetes mellitus. This study compared the nephrotoxicity of iodixanol and the LOCM ioversol in CKD patients undergoing coronary angiography. METHODS This is a prospective double-blind trial in 337 patients with...

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We compared the Swedish Coronary Angiography and Angioplasty Registry with the Swedish 'Hospital Discharge Register' to assess contrast media (CM)-induced renal failure. Hospitals used only one type CM. From 2000 to 2003, iodixanol (iso-osmolar) was used in 45 485 patients, ioxaglate (low osmolar) in 12 440 subjects. To include the earlier used CM iohexol (low osmolar), analysis extended back t...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2007

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2007.02.005